Beclomethasone dipropionate EP Impurity H-D5 CAS 5534-18-9 (Non-Labelled)
| CAS No. | 5534-18-9 (Non-Labelled) |
| Molecular Formula | - |
| Molecular Weight | 470.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Beclomethasone dipropionate EP Impurity H-D5 (CAS 5534-18-9 (Non-Labelled)) is a certified pharmaceutical impurity reference standard with the molecular formula C25H28D5ClO6 and a molecular weight of 470.01 g/mol.
The molecular framework of Beclomethasone dipropionate EP Impurity H-D5 (C25H28D5ClO6) is characterized by deuterium isotope labeling, a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H28D5ClO6 |
| Molecular Weight | 470.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Beclomethasone Standards
- Beclomethasone 17-Propionate-d5 (CAS CATO-C4X-147425)
- Beclomethasone-17-Monopropionate-d3 (CAS CATO-C4X-147426)
- Beclomethasone dipropionate Impurity 30 (CAS 2758770-17-9)
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- Beclomethasone dipropionate Impurity 23 (CAS CATO-C4X-147423)
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- Beclomethasone-d5 (CAS 1263143-48-1)
Recommended Standards
- Nefazodone (CAS 83366-66-9)
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- 4,5,5,5-tetrafluoro-4-(heptafluoroprop-1-oxy)-2-Iodopentan-1-ol (CAS 886762-19-2)
- N-(3-Chloro-2-methylphenyl)-2-({3-ethyl-4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl)acetamide (CAS 1223982-51-1)
- Mirtazapine Impurity 5 (CAS CATO-C4X-151111)
- Ruxolitinib Impurity N1 (CAS 1146629-84-6)
- Atorvastatin Impurity 84 (CAS CATO-C4X-113284)
- Sodium 2-hydroxysuccinate (CAS 63474-37-3)
- 2-Morpholinoquinazolin-4-amine (CAS 41078-28-8)
- (3S)-3-[5-(4-aminobutoxy)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2782051-23-2)
- (R)-2-Amino-2-(3,5-difluoropyridin-2-yl)ethan-1-ol (CAS 1213009-73-4)
- Tert-butyl 4-(2-fluorobenzoyl)piperazine-1-carboxylate (CAS 828298-39-1)
- 2-((3R,4S)-4-hydroxypyrrolidin-3-yl)acetonitrile hydrochloride (CAS 2227679-49-2)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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